Small Cell Prostate Cancer Clinical Trials

Research and clinical trials.

Small cell prostate cancer clinical trials.

Aggarwal identified a sub type that became prevalent in 17 of patients who were heavily pretreated with enzalutamide xtandi and abiraterone zytiga he calls this treatment emergent small cell neuroendocrine prostate cancer t scnc the pre treatment probably selected for this subtype that may be partially responsive to. But small cell prostate cancer is very rare so it is harder to research than other more common types of prostate cancer. An antigen often expressed by several different types of cancers cea. A clinical research study is now enrolling men with recurrent prostate cancer after radical prostatectomy who have a psa of at least 0 1 ng ml and are planned to undergo salvage radiotherapy.

Clinical trials look at new ways to prevent detect or treat disease. For cohort a scnc. Cancer vaccine targets under evaluation in prostate cancer clinical trials include. Doctors are always trying to improve the diagnosis and treatment of cancer.

The proposed clinical trial will study the effects of 12 months of therapy with arn 509 alone or in combination with an lhrh agonist lhrha each compared to lhrha alone in men with a rapidly rising serum psa after prior definitive local therapy for prostate cancer. Nci s basic information about clinical trials explains the types and phases of trials and how they are carried out. Non small cell lung cancer or prostate cancer that has spread to other. The eligibility criteria which is meant to ensure patients safety may include the patient s age gender cancer type and stage previous treatments and overall health.

Progression during or following completion of at least 1 prior line of systemic therapy for locally advanced or metastatic prostate cancer. The clinical trials on this list are for prostate cancer treatment. All trials on the list are supported by nci. A protein involved in cellular adhesion that is normally produced only before birth but is often abnormally expressed in cancer and may contribute to metastasis.

The purpose of this research study is to assess the impact of 68ga psma 11 pet ct an experimental imaging scan for prostate cancer on the success of. Patients with de novo small cell prostate cancer are not required to have received androgen deprivation therapy adt. Clinical trials are research studies that involve people. Not all neuroendocrine prostate cancers carry the same prognosis.

Participation is always voluntary. Subjects will be treated with mln8237 at 50 mg twice daily for 7 days repeated every 21 days.